Our mission
Bridging the gap between discovery and clinical application
The microbiome represents one of the most exciting frontiers in modern science. Our mission is to curate, connect and catalyse research that moves beyond correlation into actionable therapeutic insight.
By fostering cross-disciplinary collaboration, we help scientists and clinicians translate microbial complexity into human-health outcomes.
Featured Research & Latest News
Latest breakthroughs in microbiome studies.
Disentangling microbiota-dependent and -independent impacts of antibiotics on host physiology
Antibiotics are believed to affect host physiology by altering the gut microbiota. However, it remains unclear which effects of antibiotics are microbiota dependent and which are microbiota independent. Here we present a resource encompassing host and microbiota responses to antibiotic treatment and a computational tool with which to analyse them.
Faecalibacterium prausnitzii EXL01 Strain for the prevention of multiple-recurrent Clostridioides difficile Infection
Recurrent Clostridioides difficile infection (rCDI) results from persistent microbiome dysfunction and impaired colonization resistance. Although fecal microbiota transplantation (FMT) is effective, defined and scalable alternatives are needed. We evaluated whether a single commensal strain could restore key microbiome functions and prevent recurrence.
Maternal influences on infant gut microbiome and health
We observe that the maternal gut microbiome undergoes only subtle changes during pregnancy and postpartum, influenced by diet, infections and pre-pregnancy smoking. The maternal gut microbiome is a major reservoir for infant gut strains, with only occasional transmission from vaginal and breast milk microbiomes. Mother–infant gut strain sharing is time dependent, and higher maternal gut species abundance increases the likelihood of strain transmission. We find that the maternal gut microbiome is a predictor of infant eczema. Mode of delivery and feeding mode primarily shaped the infant gut microbiome and its functional profiles, with maternal exposures also having a role.
Interview – John Cryan
Don’t miss the interview with our MBTL 2026 Keynote Speaker, Prof. John F. Cryan from University College Cork, Ireland, as he shares his insights and perspectives on the latest developments in his field.
Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata
A deep dive into the enigmatic world of sleep, exploring its biological functions, evolutionary origins, and diverse manifestations across different species.
New gut science: 3 bacteria that keep your heart healthy | Prof. Tim Spector & Prof. Nicola Segata
There’s an unseen world within you, teeming with trillions of tiny inhabitants. Your gut microbiome contains millions of bugs. Some bugs are beneficial, while others wreak havoc, quietly disrupting your health. What if these disruptive "invasive species" are silently driving the rise of cardiometabolic diseases, the leading cause of illness in Western countries?
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